To the Editor On behalf of my coauthors, I write to report an error in our Original Investigation, “Opioid Prescribing and Outcomes in Patients with Sickle Cell Disease Post–2016 CDC Guideline,” published online on March 11, 2024, and the May 2024 issue of JAMA Internal Medicine. In this cohort study of 14 979 individuals with sickle cell disease (SCD), we reported that our interrupted time series analysis found significant downward trends in opioid prescribing practices and significant upward trends in pain-related hospitalizations after the release of the 2016 Centers for Disease Control and Prevention (CDC) guideline for prescribing opioids for chronic pain.

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